Lourdes J. Cruz, Ph.D. – National Scientist, Professor Emeritus

Contact:
lulycruzj@yahoo.com

Education:
Ph.D. Biochemistry, University of Iowa City, U.S.A.

Research Interests:
Marine Toxins, Isolation and characterization of peptides from Conus venoms, Biodiversity and drug development, Linking Science and technology to poor rural communities and indigenous tribes

Selected Publications:

• Lam HY, Enriquez MLD, Heralde, FMI, Loquias, MM, Montaño MNE, Agapito JD, Arriola AK, CruzLJ, Sia IC, Cheng KJG, Enriquez CMD, Marohomsalic HN, Yap JRD. 2018. Establishing a blueprint for nature-based products development and conservation for the Philippines. Acta Med Philipp, 52(4), 295–301.
• Subong, B. J. J., Benico, G. A., Sulit, A. K. L., Mendoza, C. O., Cruz, L. J., Azanza, R. V., & Jimenez, E. C. (2017). Toxicity and protein expression of alexandrium species collected in the philippine waters. Philippine Journal of Science, 146(4), 425–436.
• Jimenez E.C., Cruz L.J. (2017) Conotoxins as Tools in Research on Nicotinic Receptors. In: Gopalakrishnakone P., Cruz L., Luo S. (eds) Toxins and Drug Discovery. Toxinology. Springer, Dordrecht
• Cruz LJ, White J. Clinical toxicology of Conus snail stings. In: Meier J, White J, (eds) Clinical Toxicology of Animal Venoms. CRC Press, Boca Raton FL, 1995.
• Mendoza, A. D. L., Sombrito, E. Z., & Cruz, L. J. (2015). A tyrosine-containing analog of mu-conotoxin GIIIA as ligand in the receptor binding assay for paralytic shellfish poisons. Toxicon, 99, 95–101.
• Bondoc, Karen Grace, Lee, Hyeyoung, Cruz, Lourdes, Lebrilla, Carlito & Juinio-Meñez, Marie. (2014). Corrigendum to “Chemical fingerprinting and phylogenetic mapping of saponin congeners from three tropical holothurian sea cucumbers” [Comp. Biochem. Physiol. B 166 (3–4) (2013) 182–193]. Comparative Biochemistry and Physiology Part B: Biochemistry and Molecular Biology. 175.
• Cruz L.J., McIntosh J.M., Imperial J.S., Gray W.R. (2000) Conus Peptides and Their Iodinated Derivatives as Probes for Ion Channels and Receptors. In: Rochat H., Martin-Eauclaire MF. (eds) Animal Toxins. Methods and Tools in Biosciences and Medicine. Birkhäuser, Basel
• Mendoza, Christopher, C. Rabanes, Ariel, Jimenez, Elsie, Azanza, Rhodora, Cortez-Akhunzadah, Jade & Cruz, Lourdes. (2013). Detection of ciguatera fish poisoning in the Philippines. Journal of Environmental Science and Management. 16. 50-55.
• K.G. Bondoc, H. Lee, L.J. Cruz, C.B. Lebrilla, M.A. Juinio-MenezChemical fingerprinting and phylogenetic mapping of saponin congeners from three tropical holothurian sea cucumbers. Comp. Biochem. Physiol. B Biochem. Mol. Biol., 166 (2013), pp. 182-193
• Bhatia S, Kil YJ, Ueberheide B, Chait BT, Tayo L, Cruz L, Lu B, Yates JR, Bern M. 2012. Constrained de novo sequencing of conotoxins. J Prot Res11:4191–200.